Download Application of Apoptosis to Cancer Treatment by Mels Sluyser PDF

By Mels Sluyser

Novel medicinal drugs are being constructed which engage with the programmed telephone dying (apoptotic) equipment in melanoma cells, thereby inflicting those cells to devote suicide and to be faraway from the physique. study is usually directed to enquire why the melanoma cells occasionally lose the power to endure apoptosis after a undeniable time period and strategies are being built to reactivate this mobilephone demise procedure. This booklet is meant for employees within the box and clinicians as an invaluable advisor of the scenario during this fascinating box that could provide more advantageous percentages for therapy of melanoma sufferers. Mels Sluyser is the Editor of the journals APOPTOSIS and ANTI-CANCER medicines. He brings jointly a set of papers written by means of the world’s best specialists in those fields.

Show description

Read or Download Application of Apoptosis to Cancer Treatment PDF

Best oncology books

Cancer Biology

The fourth version of this vintage textual content offers an intensive, but concise assessment of the mobile and molecular mechanisms fascinated by the transformation of standard into malignant cells, the invasiveness of melanoma cells into host tissues, and the metastatic unfold of melanoma cells within the host organism. It defines the basic pathophysiologic alterations that take place in tumor tissue and within the host animal or sufferer.

High-Dose Cancer Therapy: Pharmacology, Hematopoietins, Stem Cells, 3rd edition

Univ. of Nebraska, Omaha. Reference at the simple and scientific technological know-how of dose-intensive melanoma treatment. For hematologists, oncologists, and fellows within the box. past variation: c1995. Halftone illustrations with a number of colour plates. broad references. DNLM: Neoplasms--drug remedy. additional to Brandon-Hill scientific record in April 2001.

Oncology for Palliative Medicine (Oxford Medical Publications)

Experts and nurses in palliative drugs who don't have a historical past in oncology want to know in regards to the varieties of melanoma so one can take care of palliation in those sufferers. the recent version of this renowned booklet keeps to supply complete insurance of melanoma administration geared toward palliative care pros.

Additional resources for Application of Apoptosis to Cancer Treatment

Example text

NF-kappaB inhibition restores sensitivity to Fas-mediated apoptosis in lymphoma cell lines. Ann N Y Acad Sci 2003; 1010: 232-236. 173. Semenza GL. Involvement of hypoxia-inducible factor 1 in human cancer. Intern Med 2002; 41: 79-83. 174. Shibaji T et al. Prognostic significance of HIF-1 alpha overexpression in human pancreatic cancer. Anticancer Res 2003; 23: 4721-4727. 175. Akakura N et al. Constitutive expression of hypoxia-inducible factor-1alpha renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation.

274:22739-22746. 55.

Proc Natl Acad Sci U S A 2003; 100: 1931-1936. 145. Marchenko ND, Zaika A, Moll UM. Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling. J Biol Chem 2000; 275: 1620216212. 146. Mihara M et al. p53 has a direct apoptogenic role at the mitochondria. Mol Celll 2003; 11: 577-590. 147. Danielsen AJ, Maihle NJ. The EGF/ErbB receptor family and apoptosis. Growth Factors 2002; 20: 1-15. 148. Ram TG, Ethier SP. Phosphatidylinositol 3-kinase recruitment by p185erbB-2 and erbB-3 is potently induced by neu differentiation factor/heregulin during mitogenesis and is constitutively elevated in growth factor-independent breast carcinoma cells with c-erbB-2 gene amplification.

Download PDF sample

Rated 4.55 of 5 – based on 29 votes